RESUMO
SUMMARY: The efficacy and safety of subcutaneous immunotherapy with modified, high-dose, major allergen house dust mite extract is widely supported by double-blind, placebo-controlled studies. However, little is known regarding patient-perceived efficacy and satisfaction. An observational, retrospective, multicentre study in patients treated with Acaroid® was conducted to assess the efficacy and degree of satisfaction of the patients after the first six months of treatment with it. All the clinical study procedures were performed according to the routine clinical practice. This study demonstrates that Acaroid® is effective and well tolerated. The patients' condition demonstrated a clear and marked improvement in the first 6 months after treatment initiation. Patients treated with Acaroid® were very satisfied, with a correlation to improvement in patient-perceived symptoms and the administration of treatment by a healthcare professional.
Assuntos
Satisfação do Paciente , Pyroglyphidae/imunologia , Adolescente , Adulto , Idoso , Animais , Criança , Pré-Escolar , Dessensibilização Imunológica/métodos , Humanos , Pessoa de Meia-Idade , Estudos Retrospectivos , Inquéritos e QuestionáriosAssuntos
Asma/diagnóstico , Doença Pulmonar Obstrutiva Crônica/diagnóstico , Traqueomalácia/diagnóstico , Animais , Antígenos de Dermatophagoides/imunologia , Asma/complicações , Asma/genética , Asma/imunologia , Asma/fisiopatologia , Bronquite , Tosse , Diagnóstico Diferencial , Dispneia , Feminino , Humanos , Pessoa de Meia-Idade , Poaceae , Pólen/imunologia , Pyroglyphidae , Traqueomalácia/complicações , Traqueomalácia/genética , Traqueomalácia/imunologia , Traqueomalácia/fisiopatologiaRESUMO
From the paediatric point of view, we have undertaken two Delphi studies into bronchial asthma. The first is related to the consensus known as the consensus document of the five associations. The second is more recent and has been undertaken with GEMA (the Spanish Guidelines on the Management of Asthma).The aim of this paper is to carry out a descriptive study comparing the 2 Delphi processes and to objectively assess if in some way behaviour over the past two years has changed as far as expert opinion is concerned.In the consensus document those points giving rise to most controversy were the treatment of children under three years of age and treatment with immunotherapy in allergic asthma. It is also necessary to highlight how important it was at that particular point in time to define the phenotypes of wheezing and the predictive index of asthma in children of less than 3 years of age. Of the 52 questions in the questionnaire, in 13.6% the panel of experts reached no consensus in their positions.Following GEMA the Delphi methodology, 56 questions were asked in the first round of the questionnaire, and consensus was reached in 87.5%. As regards the paediatric part relating to diagnosis and treatment in children, agreement was reached on all the questions in the first round. Agreement was reached in 8.92% questions in the second round.Clinical guidelines and consensus documents can modify behaviour towards an illness, both in the diagnosis and treatment
Assuntos
Humanos , Masculino , Feminino , Criança , Asma/diagnóstico , Asma/terapia , Conferências de Consenso como Assunto , Guias de Prática Clínica como Assunto , Projetos de Pesquisa e DesenvolvimentoRESUMO
From the paediatric point of view, we have undertaken two Delphi studies into bronchial asthma. The first is related to the consensus known as the consensus document of the five associations. The second is more recent and has been undertaken with GEMA (the Spanish Guidelines on the Management of Asthma). The aim of this paper is to carry out a descriptive study comparing the 2 Delphi processes and to objectively assess if in some way behaviour over the past two years has changed as far as expert opinion is concerned. In the consensus document those points giving rise to most controversy were the treatment of children under three years of age and treatment with immunotherapy in allergic asthma. It is also necessary to highlight how important it was at that particular point in time to define the phenotypes of wheezing and the predictive index of asthma in children of less than 3 years of age. Of the 52 questions in the questionnaire, in 13.6% the panel of experts reached no consensus in their positions. Following GEMA the Delphi methodology, 56 questions were asked in the first round of the questionnaire, and consensus was reached in 87.5%. As regards the paediatric part relating to diagnosis and treatment in children, agreement was reached on all the questions in the first round. Agreement was reached in 8.92% questions in the second round. Clinical guidelines and consensus documents can modify behaviour towards an illness, both in the diagnosis and treatment.
Assuntos
Asma/tratamento farmacológico , Asma/epidemiologia , Consenso , Imunoterapia , Guias de Prática Clínica como Assunto , Antiasmáticos/uso terapêutico , Asma/diagnóstico , Pré-Escolar , Conferências de Consenso como Assunto , Técnica Delfos , Prova Pericial , Humanos , Comunicação Interdisciplinar , Seleção de PacientesAssuntos
Asma/terapia , Gerenciamento Clínico , Adolescente , Fatores Etários , Antiasmáticos/administração & dosagem , Antiasmáticos/classificação , Antiasmáticos/uso terapêutico , Asma/classificação , Asma/epidemiologia , Asma/prevenção & controle , Criança , Pré-Escolar , Terapia Combinada , Dessensibilização Imunológica/métodos , Feminino , Hospitalização , Humanos , Lactente , Recém-Nascido , Masculino , Nebulizadores e Vaporizadores , Oxigenoterapia , Alta do Paciente , Educação de Pacientes como Assunto , Sons Respiratórios , Índice de Gravidade de Doença , EspanhaRESUMO
No disponible
No disponible
Assuntos
Criança , Humanos , Asma/terapia , Imunoterapia/métodos , Asma/diagnóstico , Asma/epidemiologia , Asma/genética , Atenção Primária à Saúde , Espanha/epidemiologia , Diagnóstico Diferencial , Agonistas Adrenérgicos/farmacologia , Corticosteroides/uso terapêuticoAssuntos
Asma/diagnóstico , Asma/terapia , Consenso , Doença Aguda , Algoritmos , Criança , Pré-Escolar , Humanos , Sons RespiratóriosRESUMO
No disponible
No disponible
Assuntos
Masculino , Feminino , Criança , Humanos , Conferências de Consenso como Assunto , Asma/diagnóstico , Asma/epidemiologia , Asma/terapia , Fenótipo , Fatores de Risco , Broncodilatadores/uso terapêutico , Corticosteroides/uso terapêutico , Imunoterapia/métodos , Nebulizadores e Vaporizadores , Sociedades Médicas/tendências , Sociedades Médicas , Técnicas ImunológicasRESUMO
No disponible
Assuntos
Criança , Adolescente , Pré-Escolar , Humanos , Asma/terapia , Antiasmáticos/uso terapêuticoAssuntos
Asma , Administração por Inalação , Adolescente , Fatores Etários , Algoritmos , Alergia e Imunologia , Antialérgicos/administração & dosagem , Antialérgicos/uso terapêutico , Antiasmáticos/administração & dosagem , Antiasmáticos/uso terapêutico , Asma/classificação , Asma/diagnóstico , Asma/epidemiologia , Asma/imunologia , Asma/terapia , Broncodilatadores/administração & dosagem , Broncodilatadores/uso terapêutico , Criança , Pré-Escolar , Terapia Combinada , Dessensibilização Imunológica , Humanos , Lactente , Nebulizadores e Vaporizadores , Fenótipo , Atenção Primária à Saúde , Encaminhamento e Consulta , Espanha/epidemiologiaRESUMO
No disponible
Assuntos
Adolescente , Criança , Pré-Escolar , Humanos , Lactente , Antialérgicos/administração & dosagem , Antialérgicos/uso terapêutico , Antiasmáticos/administração & dosagem , Antiasmáticos/uso terapêutico , Asma/classificação , Asma/diagnóstico , Asma/epidemiologia , Asma/imunologia , Asma/terapia , Nebulizadores e Vaporizadores , Administração por Inalação , Fatores Etários , Algoritmos , Alergia e Imunologia , Broncodilatadores/administração & dosagem , Broncodilatadores/uso terapêutico , Terapia Combinada , Dessensibilização Imunológica , Fenótipo , Atenção Primária à Saúde , Encaminhamento e Consulta , Espanha/epidemiologiaRESUMO
No disponible